What is CranActa
CranActa utilizes a patented extraction process to yield the purest and most effective all natural Cranberry extract with the highest bioavailability.
This proprietary blend, formulated by health care professionals, nutritionists, and researchers is a food supplement designed specifically
to assist and promote a healthy urinary tract, and to natuarally help reduce and prevent urinary tract infections (UTIs).
** This product is not intended to diagnose, treat, cure, or prevent any disease and is not intended to replace any FDA approved or physician recommended treatments.
Proprietary Blend Details
Cornsilk has been used as a remedy and treatment of chronic physical irritation in the urino-genital system including
those with cystitis and disorders such as urethritis and prostatitus in men. Bladder and urinary tract infections are
also treated by many herbalists with cornsilk.
Blueberry BenefitsBlueberry (Vaccinium) has long been recognized for its flavor, nutrition, and health benefits. For centuries the juice of blueberries has also been used for medicinal purposes: to treat coughs, as a relaxant during childbirth, and to combat the “runs” thanks to a substance contained in the berries called anthocyanin. This substance has mild antibiotic properties, especially against intestinal bacteria that causes diarrhea.
Scientists at the U.S. Department of Agriculture Human Nutrition Center have found that blueberries rank extreemly high in antioxidant benefits, compared to 40 other fresh fruits and vegetables. Antioxidants help neutralize harmful “free radicals” that can lead to cancer and other age-related diseases. The total antioxidant capacity of blueberries (24 mcgmol Trolox equivalents per gram) is twice that of spinach and three times that of oranges. This extraordinary fruit is also rich in pectin, a soluble fiber that has been shown in several research studies to be effective in lowering cholesterol.
A compound in blueberries shows promise in preliminary laboratory studies of lowering cholesterol as effectively as a commercial drug and has the potential for fewer side effects, according to a researcher with the U.S. Department of Agriculture. "The compound, pterostilbene, has the potential to be developed into a nutraceutical for lowering cholesterol, particularly for those who don't respond well to conventional drugs used for this purpose," the researcher says.
Findings were described at the 228th national meeting of the American Chemical Society, the world's largest scientific society. "We are excited to learn that blueberries, which are already known to be rich in healthy compounds, may also be a potent weapon in the battle against obesity and heart disease, which are leading killers in the U.S.," says study leader Agnes M. Rimando, Ph.D., a research chemist with the USDA's Agricultural Research Service (ARS). "I compared pterostilbene with ciprofibrate [a cholesterol-lowering drug] and found that actually pterostilbene (contained in blueberries) is a little bit better." She has already suggested that pterostilbene may have properties that protect against cancer and diabetes. A drug called ciprofibrate is used for this purpose, but it can cause muscle pain and nausea. Dr Rimando believes the blueberry compound targets the liver cell receptor more effectively.
Uva Ursi Benefits
Also used as an all natural treatment for urinary tract inflammations such as cystitis and kidney stones.
The primary compound in uva ursi is arbutin (hydroquinone derivative). The stomach absorbs and then naturally
alters uva ursi into a antimicrobial disinfactant.
Junipter Berry BenefitsJuniper berries, also known by the names Juniper Bush and Juniper Bark, are found on the evergreen juniper shrub, which grows widely throughout the Northern Hemisphere. New berries appear on mature trees in the fall, and by spring they ripen to blue. Because the berries take between two to three years to fully ripen, the same plant can have unripe green and ripe blue berries at the same time.
Traditionally, juniper was used as a diuretic and to treat problems of the kidneys and bladder. Tea made from juniper berries was recommended to ward off cystitis and other urinary tract infections.
“I think juniper does contain urinary antiseptics, although bayberry and cranberry are more famous for that,” says Dr. James A. Duke, Ph.D., a botanist and toxicology specialist with the U.S. Department of Agriculture in Beltsville, Maryland.
(do not take if you are pregnant or nursing)
** This product is not intended to diagnose, treat, cure, or prevent any disease and is not intended to replace any FDA approved or physician recommended treatments.
Cranberries, and not the acidity of cranberry juice, as previously thought—prevent infection-causing bacteria from attaching to the cells that line the urinary tract, as documented in a report published in Journal of Medicinal Food.
"Cranberries, one of only three species of fruits native to North America, has a long history of medicinal food use. Native Americans used the fruit for the treatment of bladder and kidney ailments hundreds of years ago. The article by Camesano and co-workers is a milestone in the understanding of its mechanism of action," says Sheldon S. Hendler, PhD, MD, Co-Editor-in-Chief of the Journal, and Clinical Professor of Medicine, University of California, San Diego.
D-Mannose is a natural substance with several unique characteristics that make it highly effective in supporting Urinary Tract Health by helping to prevent and even fight
UTIs (Urinary Tract Infections). Well over 80% of UTIs are caused by E. Coli bacteria in the Urinary Tract, but fortunately D-Mannose naturally forms a chemical bond with
E. Coli bacteria as proven in scientific studies. After D-Mannose forms this chemical bond with the E. Coli bacteria the bacteria is literally washed away upon urination
rather than sticking to the walls of the Urinary Tract and Bladder.
Cranberry juice has been studied and citied in many Articles, Universities, and Journals for preventing UTIs (Urinary Tract Infections). Although cranberry juice has been found
effective for Urinary Tract Health, the more effective and healthy approach is a potent and strong cranberry extract which contains a much higher concentration of the bacteria fighting
properties of cranberry juice and does not contain all the sugars and calories associated with drinking large quantities of juices. CranActa enriched with with D-Mannose is the most
effective and complete extract available. Below is a short list of just a few of the many studies showing cranberry fights UTIs and promotes Urinary Tract Health.
ScienceDaily (Jan. 10, 2008)
The remarkable healing property in cranberries stems from a heavy molecule known as non-dialyzable material or NDM. This molecule, isolated by Prof. Ofek and his colleagues, seems to coat some bodily surfaces with Teflon-like efficiency, preventing infection-causing agents from taking root.
Surprisingly, NDM appears to have no effect on some of the good bacteria in our bodies, says Prof. Ofek. His seminal research on the subject, in collaboration with Prof. Nathan Sharon from the Weizmann Institute, appeared in the world’s leading medical journal, the New England Journal of Medicine, in 1991. “We understood that there was something in cranberry juice that doesn’t let infections adhere to a woman’s bladder," Prof. Ofek says. "We figured it was a specific inhibitor and proved this to be the case.” ....
He continues, “The take-home message is that ... this fruit [has] a polyphenolic material. We still don't know its chemical formula, but it seems to target a fraction of bacteria and viruses.” Today, a cranberry research team comprised of scientists from across Israel, and headed by Professors Ofek and Weiss, are investigating the berry's healing powers. Recently, it was found that cranberry NDM may also act as an anti-cancer agent. The scientific research methods behind the research have been patented by Tel Aviv University. Prof. Ofek’s recommendation is that women drink two glasses a day to treat certain infections. And because “there is still so much we don’t know about cranberries, I would suggest that men also drink two glasses a day,” he concludes.
Researchers from Rutgers University in New Jersey and the University of Michigan discovered that regular consumption of cranberry juice cocktail may offer protection against certain antibiotic resistant bacteria that cause urinary tract infections (UTIs). Their findings were published in a research letter to the editor in the 19 June 2002 issue of the Journal of the American Medical Association (JAMA).
The scientists tested the effectiveness of cranberry juice cocktail in disabling a number of Escherichia coli (E. coli) bacteria, some of which are resistant to certain drugs. Preventing UTIs could potentially reduce the use of antibiotics, and subsequently reduce further development of antibiotic resistance.
"We found that when subjects consumed cranberry juice cocktail, their urine was capable of preventing not only susceptible, but antibiotic-resistant bacteria from attaching to the urinary tract," said Amy B. Howell, research scientist at Rutgers and lead investigator of the study. "Cranberry acts to promote flushing of these problematic bacteria from the bladder into the urine stream, which should result in a lower rate of infection."
University of Maryland Medical Center
Cranberry (Vaccinium macrocarpon) has been used as both a food and a medicine for centuries. It is native to North America and was used by Native Americans to treat bladder and kidney diseases. Early settlers from England learned to use the berry both raw and cooked for many ailments, including appetite loss, stomach problems, blood disorders, and scurvy, caused by not getting enough vitamin C. Cranberry is best known for preventing urinary tract infections (UTIs), commonly caused by bacteria known as Escherichia coli (E. coli). At first, scientists thought cranberry worked by making urine acidic enough to kill the bacteria. Now, studies show that cranberry actually prevents bacteria from attaching to the walls of the urinary tract. Strong scientific studies support using cranberry, either in capsules or as juice, for preventing -- though not treating -- UTIs.
Several studies indicate that cranberry helps prevent UTIs of the bladder and urethra (the tube that drains urine from the bladder), particularly for women who have frequent UTIs. In one study of older women, cranberry juice reduced the amount of bacteria in the bladder compared to placebo. Another study showed that younger women with a history of frequent UTIs who took cranberry capsules had fewer UTIs compared to those who took placebo.
However, studies suggest that cranberry doesn' t work once you have a UTI. That' s because in preventing UTIs, it helps keep bacteria from attaching to the urinary tract. But it's less effective once the bacteria have already attached. For this reason, cranberry is more effective at preventing UTIs than treating them. UTIs should be treated with conventional antibiotics.
Read more at: http://www.umm.edu/altmed/articles/cranberry-000235.htm#ixzz1jg97Aj6B
Dr. Michael Blue, M.D., Urologist - Progressive Laboratories Norman, OK
D-Mannose is a natural occurring simple sugar that appears to be a safe, practical alternative for the treatment of urinary tract infections (UTI's). D-Mannose is absorbed eight times slower than glucose, and when ingested, is not converted to glycogen or stored in the liver, but rather goes directly to the blood stream from the upper GI tract. Hence, D-Mannose is mostly filtered through the kidneys and routed to the bladder.
The bladder lining is comprised of polysaccharide molecules. Finger-like projections on the cell surface of E. coli b acteria adhere to these molecules, initiating an infection. In the presence of D-Mannose, E. coli preferentially attach to D-Mannose molecules forming a complex which is expelled with the next voiding.
D-Mannose probably works 80-90% of the time because the bacteria disabled by Mannose causes 80-90% of UTI's. Whereas antibiotic treatment radically changes GI bacterial populations required for good health, potentially causing fungal or gastrointestinal infections, D-Mannose removes 'bad' bacteria by attachment and voiding.
Study subjects were Dr. Michael Blue's long-term patients, who had a history of reoccurring UTI's. Subjects included 42 females (12-83 years old) and 18 males (25-71 years old). After urine culture to determine specific bacterial cause, if any, subjects were started on a D-Mannose daily regimen. Of the 42 female subjects, 24 were confirmed by culture to have a UTI. In 19 cases (~80%), E. coli was the diagnosed cause, in four, Klebsiella, and in one, mixed bacteria. In the confirmed culture group, two scoops of D-Mannose daily were given for one week. Of the 12 (50%) who returned for follow-up cultures, eight were negative. Patients indicated that the symptoms had disappeared.
Statistically, 17 of the 24 (71%) females in the confirmed-culture, D-mannose-treated group reported symptom improvement. Although three of the 24 (12.5%) were unable to be contacted, they did not return for additional treatment. Only four of 24 (17%) reported no symptom improvement after D-Mannose treatment. Those females who were not confirmed by culture to have bacterial UTI but had UTI-associated symptoms were classified into a painful-bladder-syndrome (PBS) group. Of the 18 PBS females who were treated daily with two scoops of D-Mannose, 17 (94%) reported symptom improvement, the lone exception being a subject unable to be contacted, but also not returning for treatment. Eighty percent became totally symptom free. Of the 18 male subjects, 10 were confirmed by culture to have a UTI. Seven had neurogenic bladders from spinal cord injuries, three of whom were on intermittent catheterization and four had indwelling supra-pubic tubes. Two men had been incapacitated with recurrent sepsis, retention, and obstructive uropathy. Both men underwent insertion of supra pubic tubes. Once released from the hospital, both were placed on a D-Mannose daily regimen. Improvement was suggested by their ability to avoid additional hospitalization. In the group diagnosed with E. coli-related UTI and treated with D-Mannose, significant improvement was reported. Due to the composition of the male group, few responded as dramatically as females.
FINDINGS: Consistent with existing literature, about 50% of those reporting UTI symptoms were actually confirmed by culture to possess bacterial infection. The therapeutic use of D-Mannose on acute UTI's in this study was effective in eliminating or ameliorating symptoms. In addition, 80% of the painful-bladder-syndrome group became symptom free using D-Mannose. Over the six-month study, three females with different issues showed especially noteworthy responses to D-Mannose. The first was a 50-year old female with neurogenic bladder and incontinence suffering from a monthly UTI. Endoscopically, her bladder revealed numerous areas compatible with recurrent UTI's. After three months of D-Mannose, her urine was sterile, and her bladder mucosa returned to normal. The second woman complained about bladder pain for which she had received numerous, unsuccessful therapies. After one week of D-Mannose, her pain ceased. The third woman presented an E. coli infection and pronounced structural findings in her bladder called Cystitis Cystica, all of which disappeared after three months on D-Mannose.
In conclusion, D-Mannose appears to effectively treat simple, uncomplicated UTI's.
D-Mannose for Bladder and Kidney Infections
- Dr. Jonathan Wright, MD, Tahoma Clinic
The “cell walls” of each E. coli are covered with tiny fingerlike projections. The very tips of these projections are an amino acid-sugar complex, a “glycoprotein” also called a “lectin”. E. coli “lectins” have the unfortunate (for us) capability of “sticking” the bacteria to the inside walls of our bladders and urinary tracts, so they can’t be rinsed out by urination.
Unfortunately for the E. coli, D-mannose “sticks” to E. coli lectins even better than E. coli lectins “stick” to human cells. When we take a large quantity of D-mannose, almost all of it spills into the urine through our kidneys, literally “coating” any E.coli present so they can no longer “stick” to the inside walls of the bladder and urinary tract. The E. coli are literally rinsed away with normal urination!
Why is “rinsing away” E. coli with D-mannose superior to killing them with antibiotics and anti-microbials? When an antibiotic is taken, it kills unwanted micro-organisms, but it also kills many “friendly” micro-organisms. Every woman is familiar with “yeast infections” that follow antibiotic use, as the “friendly bacteria” are killed off along with the “bad bacteria”, leaving the antibiotic-insensitive yeast to grow “out of control”. Long-term or often-repeated antibiotic use can lead to major disruptions in normal body microflora, and sometimes to major disruptions in health, especially immune system function. [It's suspected that the "killer" E. coli of recent years are "mutants" caused by persistent antibiotic feeding to animals.]
By contrast, D-mannose doesn’t kill bacteria, “friendly” or “unfriendly”. D-mannose simply helps to relocate misplaced E.coli from inside of our urinary tracts to outside. (Since D-mannose is absorbed in the upper gastrointestinal tract, it doesn’t relocate the “friendly” E. coli normally present in the colon.) D-mannose treatment of E. coli bladder and urinary tract infections is ecologically sound treatment. (The very small amounts of D-mannose metabolized by our bodies and not excreted into the urine are harmless.)